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VA/DOD Clinical Practice Guidelines

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Management of First-Episode Psychosis and Schizophrenia (SCZ) (2023)

Cover page of the guideline document.The guideline describes the critical decision points in the Management of First-Episode Psychosis and Schizophrenia (SCZ) and provides clear and comprehensive evidence based recommendations incorporating current information and practices for practitioners throughout the DOD and VA Health Care systems. The guideline is intended to improve patient outcomes and local management of patients with SCZ.

Disclaimer:This Clinical Practice Guideline is intended for use only as a tool to assist a clinician/healthcare professional and should not be used to replace clinical judgment.

About the CPG

The guideline is formatted as three algorithms with 41 evidence-based recommendations:

Module A — Primary Care Evaluation and Management of Suspected Psychosis or Possible Schizophrenia
Module B — Evaluation and Management of First-Episode Psychosis and Schizophrenia by Mental Health Providers
Module C — Pharmacotherapy for Treatment of First-Episode Psychosis and Schizophrenia

Questions about the SCZ Guideline

Retired CPG's can be found on our archive page